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KMID : 0356620070220050353
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Journal of Korean Society of Endocrinology
2007 Volume.22 No. 5 p.353 ~ p.358
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A Case of Parathyroid Adenoma Manifested as Acute Pancreatitis Accompanied Subclinical Cushing`s Syndrome due to an Adrenal Adenoma
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Lee Sang-Hoon
Cho Dong-Sik
Kim Si-Woo
Cho Yoo-jin
Cha Sung-Chul
Kim Jeong-Kwon
Park Sun-Hee
Kang Haeng-Ji
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Abstract
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The manifestation of primary hyperparathyroidism by acute pancreatitis is a rare event. Furthermore, an asymptomatic adrenal mass may incidentally be detected by abdominal computed tomography. A mass that autonomously secretes glucocorticoid without any symptom is called subclinical Cushing’s syndrome. In this study, we report a rare case of a parathyroid adenoma manifested as acute pancreatitis accompanied with subclinical Cushing’s syndrome due to an incidental adrenal mass. A 47-year-old female patient presented with acute pancreatitis and hypercalcemia had a parathyroid mass detected by neck ultrasonography and a Tc(99m)-sestamibi scan. An abdominal computed tomography revealed a 3.1 x 4.3 cm mass which was detected in the left adrenal gland. The hormonal levels showed a high serum cortisol level, low ACTH level, and a high 24 h urine free cortisol level. The low and high dose dexamethasone suppression test showed no suppression. The parathyroid and adrenal masses were resected and the laboratory findings were normalized.
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KEYWORD
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Acute pancreatitis, Parathyroid adenoma, Subclinical Cushing`s syndrome
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